KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DAB1
All Species:
28.79
Human Site:
S468
Identified Species:
79.17
UniProt:
O75553
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75553
NP_066566.3
588
63775
S468
S
R
K
P
D
Q
P
S
L
T
C
T
S
E
A
Chimpanzee
Pan troglodytes
XP_001155092
553
59609
S433
S
R
K
P
D
Q
P
S
L
T
C
T
S
E
A
Rhesus Macaque
Macaca mulatta
XP_001114475
553
59623
S433
S
R
K
P
D
Q
P
S
L
T
C
T
S
E
A
Dog
Lupus familis
XP_852920
678
73918
S558
S
R
K
P
D
Q
P
S
L
T
C
T
S
E
A
Cat
Felis silvestris
Mouse
Mus musculus
P97318
588
63559
S468
S
R
K
P
D
Q
P
S
L
T
C
T
S
E
A
Rat
Rattus norvegicus
Q8CJH2
555
59882
S435
S
R
K
P
D
Q
P
S
L
T
C
T
S
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989569
551
59825
P431
P
P
V
P
S
R
K
P
D
Q
P
S
L
S
C
Frog
Xenopus laevis
NP_001083184
556
60125
S435
L
G
E
K
E
K
K
S
V
K
D
M
F
K
D
Zebra Danio
Brachydanio rerio
NP_001035775
588
63725
S454
A
R
K
G
E
Q
P
S
L
S
C
T
T
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.7
93.3
83.4
N.A.
94.7
91.3
N.A.
N.A.
85.3
34.8
62.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
93.8
93.5
84.6
N.A.
96.4
92.5
N.A.
N.A.
88.9
51.8
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
6.6
6.6
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
20
40
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
78
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
78
0
0
0
12
% C
% Asp:
0
0
0
0
67
0
0
0
12
0
12
0
0
12
12
% D
% Glu:
0
0
12
0
23
0
0
0
0
0
0
0
0
67
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% F
% Gly:
0
12
0
12
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
78
12
0
12
23
0
0
12
0
0
0
12
0
% K
% Leu:
12
0
0
0
0
0
0
0
78
0
0
0
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
12
0
78
0
0
78
12
0
0
12
0
0
0
0
% P
% Gln:
0
0
0
0
0
78
0
0
0
12
0
0
0
0
0
% Q
% Arg:
0
78
0
0
0
12
0
0
0
0
0
0
0
0
0
% R
% Ser:
67
0
0
0
12
0
0
89
0
12
0
12
67
12
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
67
0
78
12
0
0
% T
% Val:
0
0
12
0
0
0
0
0
12
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _